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The Latest Breaking News from Genome

Whole-genome sequencing data ‘can transform cancer care with tailored therapy’

Combining clinical and genomic data creates a key resource for clinicians to better predict outcomes and tailor cancer treatments, researchers say.

The Independent UK

Some believe the 1889 Russian flu pandemic was actually caused by a coronavirus – here's why that's unlikely

COVID-19 was the first coronavirus pandemic. The original Sars virus from 2003 and the Mers virus that created a health emergency in South Korea in 2015 were both coronaviruses, but fortunately failed to turn into pandemics in the way that COVID did.

The Conversation

You had your genome sequenced and found something – now what? | Explained

On November 9 this year, researchers in Iceland published a paper in the New England Journal of Medicine by researchers in which they reported trying to address whether these incidental findings could be associated with the lifespan of an individual! Researchers pored through more than 57,000 whole genome sequences obtained…

The Hindu

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Indian Immunologicals begins construction of Rs.700 cr veterinary vaccine facility in Hyderabad’s Genome Valley

IIL starts construction of Rs.700 crore veterinary vaccine manufacturing facility in Hyderabad's Genome Valley, which is expected to create 750 direct and indirect jobs.

The Hindu

Staying alert: On the rapidly increasing spread of the JN.1 variant

There should be sustained focus on genome sequencing for novel variants and India should refrain from shaming States that report more cases or novel variants

The Hindu

JN.1: Karnataka’s nodal lab awaits eligible samples and resources for genome sequencing

BMCRI laboratory yet to resume WGS of positive samples due to lack of eligible samples & resources.

The Hindu

Karnataka to increase COVID-19 testing to 5,000 a day, issues guidelines for genome sequencing

Karnataka Health and Family Welfare Department increases testing and Whole Genome Sequencing to prepare for COVID-19 upsurge.

The Hindu

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The era of CRISPR therapeutics is here – what can we expect? | Explained

Two geneticists explain the groundbreaking CRISPR-based therapies approved for sickle-cell disease and β-thalassaemia, and other genetic therapeutics in development, including base-editing and prime-editing.

The Hindu

Study reveals new genes can arise from nothing

The human genome contains ca. 20,000 genes that are used for the construction of proteins. Actions of these classical genes are coordinated by thousands of regulatory genes, the smallest of which encode microRNA molecules that are 22 base pairs in length. Read further on Dynamite News:

Dynamite News

The unusual cabbage mutation that could boost crop yield | Explained

Deleting a single base-pair from the genome of plants like cabbage, cauliflower, broccoli, tomato, and rice can make them male-sterile, leading to an abundant harvest of hybrid seeds. This is due to a process called heterosis, which is enabled by the fine balance of the Ms-cd1 protein's levels. The mutation's…

The Hindu

The transformative benefits of population-level genome sequencing | Explained

A revolutionary shift in genomics tech has enabled population-scale sequencing, leading to unprecedented insights into humans’ genetic diversity. UK's 100K Genome project, deCODE's Icelandic effort, Diversity Human Genome Initiative, AllofUS, 1+ Million Genomes, 3M African Genomes, Emirati genome programme, GenomeAsia, IndiGen, and GenomeIndia - all aim to sequence lakhs of…

The Hindu

UK Biobank releases world’s largest set of whole genome sequencing data

Among other things, the data could enable researchers to look at a person’s individual risk of common disease.

The Independent UK

MicroRNA is the master regulator of the genome − researchers are learning how to treat disease by harnessing the way it controls genes

The Earth formed 4.5 billion years ago, and life less than a billion years after that. Although life as we know it is dependent on four major macromolecules – DNA, RNA, proteins and lipids – only one is thought to have been present at the beginning of life: RNA.

The Conversation

The unusual ‘mutations’ that protect humans from viruses | Explained

Paramutations protect humans against viruses and are triggered by piRNA clusters, which are 3% of the fruit fly genome. Paramutations involve a small chemical modification of a chromosomal protein, flipping a nearby gene into a silenced state. William Bateson and Caroline Pellew discovered the first paramutation in the culinary pea…

The Hindu

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Salon

A Thanksgiving hero: the cranberry

"Cranberries' close association with Thanksgiving was simply a practical matter at first"

The Conversation

Cranberries can bounce, float and pollinate themselves: The saucy science of a Thanksgiving classic

Cranberries are a staple in U.S. households at Thanksgiving – but how did this bog dweller end up on holiday tables?

The Independent UK

Scientists create baker’s yeast with more than 50% synthetic DNA

The overarching aim was to build a yeast that can teach us new biology, researchers said.

The Hindu

The Zika genome and insights in the era of emerging outbreaks

Zika and dengue viruses infect up to 400 million people annually. Genomic studies of Zika have revealed its spread, diagnosis, epidemiology, and pathogenesis. Recent studies have found that viral load and DENV infections influence microcephaly following Zika infections. Zika and DENV interactions can also increase the severity of dengue disease.

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The Hindu

NIAB scientists design a vaccine candidate against LSD virus

The Hindu

How bat genomes provide insights into immunity and cancer

The COVID-19 pandemic cast a bright spotlight on the habits of bats. Over the years, researchers have unearthed significant insights by sequencing the genomes of many bat species.

The Hindu

Avian influenza viruses undergo major evolutionary changes

H5N1 virus activity has intensified globally since 2021, posing risk to humans. A study in Nature reveals a shift in the epicentre of these viruses from Asia to Africa and Europe. Analysis of 10,000 viral genomes and epidemiological data shows new strains have evolved through genetic reassortment. Findings suggest persistence…

The Independent UK

How Neanderthal DNA got ‘diluted’ among Europeans finally found

‘Genomes of farmers from Anatolia diluted Neanderthal DNA a little more’

The Conversation

Wild plants may edit their genomes in the same way we make GM crops – and it could be crucial to evolution

Genetically modified (GM) crops may be controversial, but similar processes happen naturally with wild plants. However, scientists have long been puzzled about how these processes happen. Our recent study may help researchers solve the mystery.

The Conversation

There are 750 unidentified human remains in Australia. Could your DNA help solve one of these cold cases?

Yesterday it was announced the Australian Federal Police (AFP) National DNA Program for Unidentified and Missing Persons used advanced DNA technology to assist South Australia Police resolve a 40-year-old missing persons case.

The Hindu

NIAB scientists decode genome of indigenous cattle

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